Central Lines in the Neonate

Learn about the different types of central venous catheters used in neonatal patients and how to provide evidence-based care to the neonate with a central line.

Published | 1 min. read
Quick Takes

  • CNE credit available
  • Updated version released Nov. 2025, reviewed every 3 years

Central venous catheters (CVCs) are an essential access device for patients in the Neonatal Intensive Care Unit (NICU). Early CVC placement preserves vessels and reduces the number of venipuncture attempts. CVCs are commonly inserted in neonates for infusion of medications and solutions that could damage peripheral veins, blood pressure monitoring and blood sampling. This course discusses the types of CVCs commonly used in the neonate, device selection and insertion, care and maintenance, ongoing assessment, and prevention and management of complications.

Upon course completion, learners should be able to describe the different types of central venous catheters used in neonatal patients and provide evidence-based care to the neonate with a central line.

Objectives

  • Explain why central venous catheters (CVCs) are necessary for patients in the NICU
  • Identify types of CVCs used in the neonatal population
  • Apply the steps of the insertion and maintenance bundles
  • Recognize complications associated with CVCs
  • Follow evidence-based measures to prevent and manage central line-associated complications
  • Identify strategies to safely support neurodevelopmental care practices in neonates with central venous catheters
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Key Features

  • Real patient images of neonatal central lines to improve clinical recognition, accuracy, and bedside application
  • Patient scenario of an infant with a central line and associated challenges to strengthen clinical judgment and effective mitigation of complications
  • Detailed review of risk factors, prevention strategies, early warning signs, and evidence-based treatment for common complications seen with CVCs

Learn more about this course and see related courses on the Pediatric Learning Solutions Neonatal Intensive Care Unit Library page.

NOTE: This course is only available to staff at PLS-participating hospitals and health systems through their organization’s Learning Management System. Please check with your hospital’s education team or contact Patty Kohn to learn more.

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